OraGen® Viable Dental Bone Allograft

OraGen^® is a viable allograft combining osteogenic cells, osteoconductive corticocancellous chips, and osteoinductive demineralized bone matrix – supporting successful bone remodeling². Clinically proven for effectiveness in promoting strong, stable bone regeneration, OraGen provides periodontists and oral surgeons with a reliable, advanced bone grafting solution – even in complex cases^1-4.

1. Shahrdar C, McLean J, Gianulis E, et al. Clinical outcome and explant histology after using a cellular bone allograft in two-stage total hip arthroplasty. . J Orthop Surg Res. 2020;15(1):16. doi:10.1186/s13018-020-1542-x Article in Review.
2. Gianulis et al. Cell and Tissue Banking (2022) E-pub ahead of print. Doi: 10.1007/s10561-022-10044-2Khan SN, Cammisa FP, Jr., Sandhu HS, Diwan AD, Girardi FP, Lane JM. The biology of bone grafting. J Am Acad Orthop Surg. 2005; 13(1):77-86. https:// doi.org/10.1097/00005131-189809000-0002.
3. Marschall, J. S., Davis, S. S., Jones, L., & Kushner, G. M. Are Cellular Bone Matrix Allografts a Viable Option for Mandibular Tissue Engineering and Reconstruction. Journal of Oral and Maxillofacial Surgery. https://doi.org/10.1016/j.joms.2024.05.040.
4. Tentindo, G. (a), Brown K, Gianulis E (b), Softic D (b), Qui X (b). Histology of ViviGen® Mandibular Clinical Explant Reveals Extensive Bone Formation in a Patient with Chronic Osteomyelitis. (a) Oral Facial Surgery Institute, 621 S New Ballas Rd, Saint Louis, MO, USA; (b) LifeNet Health, 1864 Concert Dr., Virginia Beach, VA, USA